Física o Química was a Spanish television series made by Antena 3. The first episode premiered on 4 February 2008.
Before its televised broadcast, Física o Química was released on cell phones in Vodafone live! and on the official website of Antena 3. After the success of the first season, which ended on 31 March 2008, Antena 3 announced the filming of a new season which would feature more episodes and few cast changes. The second season premiered on 8 September 2008, with guest appearances by Michel Brown and María Casal, among others; it ended on 8 December 2008. The third season premiered on 13 April 2009 and included new characters portrayed by Óscar Sinela, Sandra Blázquez, Miriam Giovanelli, Adrián Rodríguez, Irene Sánchez and José Manuel Seda, and the entry of character actor Álex Barahona who had already appeared on the show, thus compensating for the departure of Michel Brown, Andrés Cheung, Karim El-Kerem and Xavi Mira. Antena 3 confirmed the filming of the fourth season with Adrián Rodríguez as a regular character and the return of Leonor Martín.
Física o Química started its seventh season with the departure of Nuria González, Úrsula Corberó, Angy Fernández and José Manuel Seda. Filming began on 28 February 2011. In May 2011 the series was cancelled due to a fall in viewing figures. On 1 June 2011, the death of a main character caused considerable outcry on the Antena 3 website.